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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIK3R6
All Species:
8.48
Human Site:
S628
Identified Species:
26.67
UniProt:
Q5UE93
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5UE93
NP_001010855.1
754
84258
S628
P
A
S
D
T
E
V
S
G
S
S
H
C
P
L
Chimpanzee
Pan troglodytes
XP_001165830
880
97328
K758
C
T
S
V
N
L
N
K
A
C
R
K
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001118224
721
80384
S595
P
A
S
D
T
E
V
S
G
S
R
H
C
P
L
Dog
Lupus familis
XP_850280
763
84802
S638
P
A
S
D
T
E
V
S
G
P
T
H
T
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U6Q4
756
84644
G631
A
G
D
T
E
V
S
G
F
F
H
C
T
S
P
Rat
Rattus norvegicus
NP_001074913
756
84620
G631
A
G
D
T
E
V
S
G
F
S
H
C
T
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIB8
881
98356
A763
T
S
V
N
L
S
K
A
C
K
K
Y
E
E
L
Frog
Xenopus laevis
Q6INI0
879
98911
S734
L
Q
I
V
Y
S
K
S
T
V
S
G
R
S
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24
90.4
84.9
N.A.
82.8
82.1
N.A.
N.A.
21.6
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.5
92.8
89.2
N.A.
89.1
88.6
N.A.
N.A.
39.6
40.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
73.3
N.A.
0
6.6
N.A.
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
93.3
80
N.A.
0
6.6
N.A.
N.A.
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
38
0
0
0
0
0
13
13
0
0
0
0
0
0
% A
% Cys:
13
0
0
0
0
0
0
0
13
13
0
25
25
0
0
% C
% Asp:
0
0
25
38
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
25
38
0
0
0
0
0
0
13
25
13
% E
% Phe:
0
0
0
0
0
0
0
0
25
13
0
0
0
0
0
% F
% Gly:
0
25
0
0
0
0
0
25
38
0
0
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
25
38
0
0
0
% H
% Ile:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
25
13
0
13
13
13
0
0
0
% K
% Leu:
13
0
0
0
13
13
0
0
0
0
0
0
0
0
38
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
13
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
38
0
0
0
0
0
0
0
0
13
0
0
0
38
38
% P
% Gln:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
25
0
13
0
13
% R
% Ser:
0
13
50
0
0
25
25
50
0
38
25
0
0
38
0
% S
% Thr:
13
13
0
25
38
0
0
0
13
0
13
0
38
0
0
% T
% Val:
0
0
13
25
0
25
38
0
0
13
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _